Posted: May 22nd, 2023

Information on the pathogenesis of human babesiosis

In vitro experiments and studies on B. microti using animal models (mice and cattle) provide information on the pathogenesis of human babesiosis. It is shown from such studies that cellular immunity has an upper hand over humoral immunity in containing babesiosis (Hunfeld et al. 1227). This is evident in mice experiments where T helper cells play a significant role in keeping parasitemia under control. These findings are consistent with the inability of immunocompromised patients to control unrelenting parasitemia. In the same way, a reduction of natural killer cells and macrophages makes individuals more vulnerable to babesiosis infection. All these findings lead to the conclusion that the pathobiology of babesiosis is not a consequence of the parasite, but the host immune response.

Splenectomy, which is the surgical removal of the spleen, increases the risk of babesiosis. This is because the spleen performs a crucial function in host protection by eliminating infected red blood cells from the bloodstream. In addition, the spleen is a secondary lymphoid organ and participates in intensifying a protective immune rejoinder.

Don't use plagiarized sources. Get Your Custom Essay on
Information on the pathogenesis of human babesiosis
Just from $13/Page
Order Essay

Expert paper writers are just a few clicks away

Place an order in 3 easy steps. Takes less than 5 mins.

Calculate the price of your order

You will get a personal manager and a discount.
We'll send you the first draft for approval by at
Total price:
Open chat
Need assignment help? You can contact our live agent via WhatsApp using +1 718 717 2861

Feel free to ask questions, clarifications, or discounts available when placing an order.